Search on: NODAL SIGNALING PROTEINS 
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Descriptor English:   Nodal Signaling Ligands 
Descriptor Spanish:   Ligandos de Señalización Nodal 
Descriptor Portuguese:   Ligantes da Sinalização Nodal 
Synonyms English:   Nodal Signaling Proteins
Signaling Proteins, Nodal  
Tree Number:   D12.644.276.954.550
D12.776.467.942.550
D23.529.942.550
Definition English:   Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE. 
History Note English:   2009 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53145 
Unique Identifier:   D055456 

Occurrence in VHL:
 

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